Budget impact analysis of routinely using whole-genomic sequencing of six multidrug-resistant bacterial pathogens in Queensland, Australia

Objective To predict the cost and health effects of routine use of whole-genome sequencing (WGS) of bacterial pathogens compared with those of standard of care.Design Budget impact analysis was performed over the following 5 years.Data were primarily from sequencing results on clusters of multidrug-resistant organisms across 27 hospitals.Model inpu

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Large-scale atomistic simulations of nanostructured materials based on divide-and-conquer density functional theory

A linear-scaling algorithm based on a divide-and-conquer (DC) scheme is designed to perform large-scale molecular-dynamics simulations, in which interatomic forces are computed quantum mechanically in the framework axle hub Assembly of the density functional theory (DFT).This scheme is applied to the thermite reaction at an Al/Fe2O3 interface.It is

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